Project

Promoting axon regeneration in living organisms has long been the dream of neuroscientists which this project would address. In NEMESIS project, we will use a magneto-switch for guiding axon growth. The magneto-switches can generate forces at the level of microtubules that triggers a mechanotransduction pathway, resulting in axon elongation and synaptic maturation.
The NEMESIS project will demonstrate the ability to guide axon elongation, counteracting repelling cues, and to control axon navigation in a living organism (e.g., promoting reinnervation of neurons from the brain to the spinal cord). If the project will be successful, the magneto-switch will be a new tool for promoting axon regeneration in the central nervous system.

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